This manneristic building encloses the long and narrow Piazzale degli Uffizi. It was built for Cosimo I to house his administrative and judicial offices. It was begun by Giorgio Vasari (1560) and finished in 1585 by Bernardo Buontalenti and Alfonso Parigi. Both Cosimo I and Giorgio Vasari died in 1574. Already in 1581 Francesco I set up the Gallery with pictures, statues and other precious things. The Uffizi building was inspired by the architecture of the Laurentian Library. The sculptures and the niches of the pillars represent famous Tuscans and they have been added from the 19th century. Two of them are Saint Antonino by Giovanni Dupré (1854) and Niccolò Macchiavelli by Lorenzo Bartolini.
Remains of the Romanesque church of San Piero Scheraggio can be seen at the ground floor. It was already partially demolished in 1410 to enlarge via della Ninna. It used to be of the community councils. Here Dante e Boccaccio made speeches to the public. The Mind building is only partial visible. The Door of the Supplications is by Bernardo Buontalenti. It is surmounted by a bust of Cosimo I attributed to Giovanni Bandini.
The houses of the Pulci, are now the seat of the Georgofili, one of the oldest institutions for the study of the economic and agrarian sciences.
The State Archives have been housed in the Uffizi Gallery until recent times. They are found in Viale Giovine Italia n. 6. They comprised documents relating to the history of Florence in Tuscany. They also include an exposition of documents and curiosities regarding Florence and Italy. Some famous documents are: the Fiorinaio (register of the Florentine Mint; the charter of union between the Greek and Latin churches (1439); the book of the Chiodo, containing the condemnation of Dante as well as many nautical maps. The entrance to the gallery is flanked by the 19th century statues of Lorenzo the Magnificent and the Cosimo the Elder.
The Galleria dell'Accademia was founded in 1784 by Pietro Leopoldo. He getting together various institutions including the ancient Academy of Design Arts, founded in 1563 by Cosimo I de 'Medici.
In the Sala del Colosso there are many Italian artists such as Sandro Botticelli, Domenico Ghirlandaio, Perugino and many others.
The Prisons Gallery takes its name from to the four sculptures of male nudes, called Prisoners, made by Michelangelo for the tomb of Julius II.
Tribuna del David - the room houses from 1873 to Michelangelo's David, built between 1501-04 and it’s from Piazza della Signoria.
Gipsoteca Bartolini (19th century Room) is a collection of paintings and sculptures by artists of the 19th century in connection with the Academy of Fine Arts, including the plaster casts by Lorenzo Bartolini.